Clarithromycin susceptibility testing of Mycobacterium avium complex using 2,3-diphenyl-5-thienyl-(2)-tetrazolium chloride microplate assay with middlebrook 7H9 broth

Young Kil Park, Won Jung Koh, Shin Ok Kim, Sonya Shin, Bum Joon Kim, Sang Nae Cho, Sun Min Lee, Chulhun L. Chang

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A series of 119 Mycobacterium avium complex isolates were subjected to clarithromycin susceptibility testing using microplates containing 2,3-diphenyl-5-thienyl-(2)-tetrazolium chloride (STC). Among 119 isolates, 114 (95.8%) were susceptible to clarithromycin and 5 were resistant according to the new and the standard method. STC counts the low cost and reduces the number of procedures needed for susceptibility testing.

Original languageEnglish
Pages (from-to)511-512
Number of pages2
JournalJournal of Korean Medical Science
Issue number3
StatePublished - 1 Jun 2009


  • Clarithromycin
  • Microtiter method
  • Mycobacterium avium complex
  • Susceptibility testing
  • Tetrazolium

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