Chronic graft versus host disease with small bowel obstruction after unrelated hematopoietic stem cell transplantation in a patient with acute myeloid leukemia

Ju Young Yoon, Hyery Kim, Hyoung Jin Kang, Kyung Duk Park, Hee Young Shin, Hyo Seop Ahn

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

Chronic graft versus host disease (GVHD) is a frequent complication after allogeneic hematopoietic stem cell transplantation (HSCT), but simultaneous small bowel obstruction is rare. Here, we report a child with acute myeloid leukemia who received an allogeneic HSCT from an unrelated matched donor. After HSCT, the patient developed severe chronic GVHD involving the small intestine, leading to obstruction of the terminal ileum. Small bowel resection was performed, and the symptoms improved without severe complications. Bowel obstruction should be considered as a possible complication of chronic GVHD; surgery may be a valuable corrective measure.

Original languageEnglish
Pages (from-to)142-145
Number of pages4
JournalKorean Journal of Hematology
Volume47
Issue number2
DOIs
StatePublished - 1 Jun 2012

Keywords

  • Acute myeloid leukemia
  • Graft versus host disease
  • Hematopoietic stem cell transplantation
  • Intestinal obstruction

Cite this