Characterization and validation of multimodal annihilation-gamma/near-infrared/visible laparoscopic system

Seong H. Song, Han G. Kang, Young B. Han, Ho Young Lee, Dae H. Jeong, Soo M. Kim, Seong J. Hong

Research output: Contribution to journalArticle

Abstract

Minimally invasive robotic surgery using fluorescence-guided images with a video laparoscope has been widely used because of its advantages of small incision, fast recovery time, and efficiency. However, the penetration depth limitation of fluorescence is a disadvantage caused by the absorption and scattering in tissues and blood cells. If this limitation can be overcome by additional imaging modalities, the surgical procedure can be quite efficient and precise. High-energy annihilation-gamma photons have a stronger penetration capability than visible and fluorescence photons. To characterize and validate a multimodal annihilation-gamma/near-infrared (NIR)/visible laparoscopic imaging system, an internal detector composed of an annihilation-gamma detector and an optical system was assembled inside a surgical stainless pipe with an outer diameter of 15.8 mm and an external detector with a dimension of 100 × 100 mm2 placed at the opposite side of the internal detector. Integrated images of 511-keV gamma rays, NIR fluorescence, and visible light were obtained simultaneously. The 511-keV gamma image could be clearly seen with the acquisition of 5 s, while NIR and visible images could be presented in real time. This multimodal system has the potential for improving the surgery time and the quality of patient care.

Original languageEnglish
Article number096008
JournalJournal of Biomedical Optics
Volume24
Issue number9
DOIs
StatePublished - 1 Sep 2019

Fingerprint

Fluorescence
Infrared radiation
Detectors
fluorescence
detectors
surgery
penetration
Photons
Laparoscopy
blood cells
photons
robotics
Optical systems
Gamma rays
Imaging systems
Surgery
acquisition
Blood
recovery
Pipe

Keywords

  • fluorescence imaging
  • minimally invasive robotic surgery
  • multimodal imaging system
  • positron emission tomography

Cite this

Song, Seong H. ; Kang, Han G. ; Han, Young B. ; Lee, Ho Young ; Jeong, Dae H. ; Kim, Soo M. ; Hong, Seong J. / Characterization and validation of multimodal annihilation-gamma/near-infrared/visible laparoscopic system. In: Journal of Biomedical Optics. 2019 ; Vol. 24, No. 9.
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Characterization and validation of multimodal annihilation-gamma/near-infrared/visible laparoscopic system. / Song, Seong H.; Kang, Han G.; Han, Young B.; Lee, Ho Young; Jeong, Dae H.; Kim, Soo M.; Hong, Seong J.

In: Journal of Biomedical Optics, Vol. 24, No. 9, 096008, 01.09.2019.

Research output: Contribution to journalArticle

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