Cancer genomics object model: An object model for multiple functional genomics data for cancer research

Yu Rang Park, Hye Won Lee, Sung Bum Cho, Ju Han Kim

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Abstract

The development of functional genomics including transcriptomics, proteomics and metabolomics allow us to monitor a large number of key cellular pathways simultaneously. Several technology-specific data models have been introduced for the representation of functional genomics experimental data, including the MicroArray Gene Expression-Object Model (MAGE-OM), the Proteomics Experiment Data Repository (PEDRo), and the Tissue MicroArray-Object Model (TMA-OM). Despite the increasing number of cancer studies using multiple functional genomics technologies, there is still no integrated data model for multiple functional genomics experimental and clinical data. We propose an object-oriented data model for cancer genomics research, Cancer Genomics Object Model (CaGe-OM). We reference four data models: Functional Genomic-Object Model, MAGE-OM, TMAOM and PEDRo. The clinical and histopathological information models are created by analyzing cancer management workflow and referencing the College of American Pathology Cancer Protocols and National Cancer Institute Common Data Elements. The CaGe-OM provides a comprehensive data model for integrated storage and analysis of clinical and multiple functional genomics data.

Original languageEnglish
Title of host publicationMEDINFO 2007 - Proceedings of the 12th World Congress on Health (Medical) Informatics
Subtitle of host publicationBuilding Sustainable Health Systems
PublisherIOS Press
Pages1235-1239
Number of pages5
ISBN (Print)9781586037741
StatePublished - 1 Jan 2007
Event12th World Congress on Medical Informatics, MEDINFO 2007 - Brisbane, QLD, Australia
Duration: 20 Aug 200724 Aug 2007

Publication series

NameStudies in Health Technology and Informatics
Volume129
ISSN (Print)0926-9630
ISSN (Electronic)1879-8365

Other

Other12th World Congress on Medical Informatics, MEDINFO 2007
CountryAustralia
CityBrisbane, QLD
Period20/08/0724/08/07

Keywords

  • cancer
  • data model
  • genomics
  • standards

Fingerprint Dive into the research topics of 'Cancer genomics object model: An object model for multiple functional genomics data for cancer research'. Together they form a unique fingerprint.

  • Cite this

    Park, Y. R., Lee, H. W., Cho, S. B., & Kim, J. H. (2007). Cancer genomics object model: An object model for multiple functional genomics data for cancer research. In MEDINFO 2007 - Proceedings of the 12th World Congress on Health (Medical) Informatics: Building Sustainable Health Systems (pp. 1235-1239). (Studies in Health Technology and Informatics; Vol. 129). IOS Press.