Bioartificial esophagus: Where are we now?

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Abstract

The current treatments for esophageal diseases, such as carcinomas, trauma or congenital malformations, require surgical intervention and esophageal reconstruction using redundant parts of the gastrointestinal tract. However, the use of gastrointestinal segments can cause various surgical morbidities and mortality because additional abdominal surgery may be required at the expense of other anatomic structures. Therefore, tissue engineering using various biomaterial or cell sources has emerged as an alternative strategy of biomimicking the native esophageal tissue that could be implanted as an artificial graft. Although tissue engineering techniques have promise as an effective regenerative strategy, no functional solution currently exists for esophageal reconstruction. Here, we present a review of the progress made in the field of regenerative medicine for esophageal reconstruction from bench to bedside.

Original languageEnglish
Title of host publicationAdvances in Experimental Medicine and Biology
PublisherSpringer New York LLC
Pages313-332
Number of pages20
DOIs
StatePublished - 1 Jan 2018

Publication series

NameAdvances in Experimental Medicine and Biology
Volume1064
ISSN (Print)0065-2598
ISSN (Electronic)2214-8019

Fingerprint

Tissue Engineering
Tissue engineering
Esophagus
Esophageal Diseases
Regenerative Medicine
Biocompatible Materials
Grafts
Surgery
Gastrointestinal Tract
Tissue
Morbidity
Carcinoma
Transplants
Mortality
Wounds and Injuries

Keywords

  • Decellularized extracellular matrix
  • Epithelial cell
  • Esophagus
  • Scaffold
  • Smooth muscle cell
  • Synthetic polymer
  • Tissue engineering

Cite this

Chung, E-J. (2018). Bioartificial esophagus: Where are we now? In Advances in Experimental Medicine and Biology (pp. 313-332). (Advances in Experimental Medicine and Biology; Vol. 1064). Springer New York LLC. https://doi.org/10.1007/978-981-13-0445-3_19
Chung, Eun-Jae. / Bioartificial esophagus : Where are we now?. Advances in Experimental Medicine and Biology. Springer New York LLC, 2018. pp. 313-332 (Advances in Experimental Medicine and Biology).
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Chung, E-J 2018, Bioartificial esophagus: Where are we now? in Advances in Experimental Medicine and Biology. Advances in Experimental Medicine and Biology, vol. 1064, Springer New York LLC, pp. 313-332. https://doi.org/10.1007/978-981-13-0445-3_19

Bioartificial esophagus : Where are we now? / Chung, Eun-Jae.

Advances in Experimental Medicine and Biology. Springer New York LLC, 2018. p. 313-332 (Advances in Experimental Medicine and Biology; Vol. 1064).

Research output: Chapter in Book/Report/Conference proceedingChapter

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Chung E-J. Bioartificial esophagus: Where are we now? In Advances in Experimental Medicine and Biology. Springer New York LLC. 2018. p. 313-332. (Advances in Experimental Medicine and Biology). https://doi.org/10.1007/978-981-13-0445-3_19