Assessment of deceased donor kidneys using a donor scoring system

Kitae Bang, Han Kyu Lee, Wooseong Huh, Yu Ji Lee, Byun Seung Woon, Han Ro, Young Hwan Hwang, Jongwon Ha, Myoung Hee Park, Sung Joo Kim, Su Kil Park, Ha Young Oh, Jaeseok Yang, Curie Ahn

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

Purpose: Marginal grafts should be used more actively in Asian countries where deceased donor transplantation is unpopular. We modified a quantitative donor scoring system proposed by Nyberg and his colleagues and developed a donor scoring system in order to assess the quality of deceased donor grafts and their prognostic value as an initial effort to promote usage of marginal donors. Materials and Methods: We retrospectively evaluated 337 patients. Results: A scoring system was derived from six donor variables [age, 0-25; renal function, 0-4; history of hypertension, 0-4; Human Leukocyte Antigen (HLA) mismatch, 0-3; body weight, 0- 1; cause of death, 0-3 points]. Donor grafts were stratified by scores: grade A, 0-10; grade B, 11-20; grade C, 21-30; and grade D, 31-40 points. Donor grades significantly correlated with estimated glomerular filtration rate (eGFR) at 6 months (A, 64.0 mL/min/1.73 m2; B, 57.0 mL/min/1.73 m2; C, 46.8 mL/min/1.73 m2; p < 0.001). The five-year graft survival rate was also lower in grade C than grade A (74% vs. 93%, p = 0.002). Donors in grade C and D were regarded as marginal donors. The proportion of marginal donors was much lower in Korea, compared with data from the United Network for Organ Sharing (15.2% vs. 29%). Conclusion: Considering the scarcity of deceased donor kidneys and the relatively better graft outcome with lower grade-donors in Korea, it is worth increasing the usage of marginal grafts.

Original languageEnglish
Pages (from-to)870-876
Number of pages7
JournalYonsei Medical Journal
Volume51
Issue number6
DOIs
StatePublished - 1 Nov 2010

Keywords

  • Cadaver
  • Donor selection
  • Kidney transplantation

Cite this

Bang, K., Lee, H. K., Huh, W., Lee, Y. J., Woon, B. S., Ro, H., Hwang, Y. H., Ha, J., Park, M. H., Kim, S. J., Park, S. K., Oh, H. Y., Yang, J., & Ahn, C. (2010). Assessment of deceased donor kidneys using a donor scoring system. Yonsei Medical Journal, 51(6), 870-876. https://doi.org/10.3349/ymj.2010.51.6.870