Application of a Small Molecule Radiopharmaceutical Concept to Improve Kinetics

Research output: Contribution to journalEditorial

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Abstract

Recently, large molecules or nanoparticles are actively studied as radiopharmaceuticals. However, their kinetics is problematic because of a slow penetration through the capillaries and slow distribution to the target. To improve the kinetics, a two-step targeting method can be applied by using small molecules and very rapid copper-free click reaction. Although this method might have limitations such as internalization of the first targeted conjugate, it will provide high target-to-non-target ratio imaging of radiopharmaceuticals.

Original languageEnglish
Pages (from-to)99-101
Number of pages3
JournalNuclear Medicine and Molecular Imaging
Volume50
Issue number2
DOIs
StatePublished - 1 Jun 2016

Bibliographical note

Publisher Copyright:
© 2015, Korean Society of Nuclear Medicine.

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