Animal Models for Tendon and Ligament

Cheol yong Park, Chris Hyunchul Jo

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Tendon and ligament disorders are common and lead to significant disability, pain, healthcare cost, and lost productivity. To study the pathogenesis and management strategies of tendon and ligament injury, appropriate choice and analysis of research models is essential. A number of animal models for tendon and ligament injuries are designed to mimic distinct clinical diseases to better evaluate underlying mechanisms and potential treatments. In this review, we discuss the common methods used for inducing animal models related to tendon and ligament injury as well as the variables for assessing outcome that may be used in animal researchs.
Original languageAmerican English
Pages (from-to)74-83
JournalJournal of Korean Orthopaedic Research Society
Volume18
StatePublished - Dec 2015

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Tendon Injuries
Ligaments
Tendons
Animal Models
Health Care Costs
Pain
Research
Therapeutics

Cite this

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Animal Models for Tendon and Ligament. / Park, Cheol yong; Jo, Chris Hyunchul.

In: Journal of Korean Orthopaedic Research Society, Vol. 18, 12.2015, p. 74-83.

Research output: Contribution to journalArticleResearchpeer-review

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AB - Tendon and ligament disorders are common and lead to significant disability, pain, healthcare cost, and lost productivity. To study the pathogenesis and management strategies of tendon and ligament injury, appropriate choice and analysis of research models is essential. A number of animal models for tendon and ligament injuries are designed to mimic distinct clinical diseases to better evaluate underlying mechanisms and potential treatments. In this review, we discuss the common methods used for inducing animal models related to tendon and ligament injury as well as the variables for assessing outcome that may be used in animal researchs.

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