An electrokinetic device for selective preconcentration and online collection based on ion concentration polarization

J. Choi; K. Huh; D. J. Moon; J. H. Chae; H. C. Kim; J. W. Hong; S. J. Kim

doi:10.1109/TRANSDUCERS.2015.7180903

An electrokinetic device for selective preconcentration and online collection based on ion concentration polarization

J. Choi, K. Huh, D. J. Moon, J. H. Chae, H. C. Kim, J. W. Hong, S. J. Kim

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

1 Scopus citations

Abstract

This paper reports a micro/nanofluidic device performing selective preconcentration and collection of two different charged molecules with different physicochemical properties using ion concentration polarization (ICP). By the balance between electroosmotic drag force and electrophoretic force on the molecules, two different dyes were highly preconcentrated and separated simultaneously. With the repeated geometry, ion depletion zone was stabilized and the selectively preconcentrated plug was well-defined. For subsequent on-chip or off-chip applications, pneumatic microvalve system was integrated and helped to collect the selectively preconcentrated plug into another location in a single solution. Alexa Fluor 488 was collected more than 30-fold within 30 minutes from the original sample mixture of Sulforhodamine B and Alexa Fluor 488 without further diffusion or dispersions. This integrated device provided the potential of selective preconcentration system to be used for online analytical system such as point-of-care applications.

Original language	English
Title of host publication	2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	228-231
Number of pages	4
ISBN (Electronic)	9781479989553
DOIs	https://doi.org/10.1109/TRANSDUCERS.2015.7180903
State	Published - 5 Aug 2015
Event	18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015 - Anchorage, United States Duration: 21 Jun 2015 → 25 Jun 2015

Publication series

Name	2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015

Other

Other	18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015
Country/Territory	United States
City	Anchorage
Period	21/06/15 → 25/06/15

Bibliographical note

Publisher Copyright:
© 2015 IEEE.

Keywords

Ion concentration polarization
electrokinetics
electroosmosis
electrophoresis
microfluidics
nanofluidics
pneumatic microvalve
preconcentration and separation of molecules

Access to Document

10.1109/TRANSDUCERS.2015.7180903

Cite this

Choi, J., Huh, K., Moon, D. J., Chae, J. H., Kim, H. C., Hong, J. W., & Kim, S. J. (2015). An electrokinetic device for selective preconcentration and online collection based on ion concentration polarization. In 2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015 (pp. 228-231). Article 7180903 (2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/TRANSDUCERS.2015.7180903

Choi, J. ; Huh, K. ; Moon, D. J. et al. / An electrokinetic device for selective preconcentration and online collection based on ion concentration polarization. 2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015. Institute of Electrical and Electronics Engineers Inc., 2015. pp. 228-231 (2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015).

@inproceedings{aac057a8a11544b2ae50430f1b5cfe03,

title = "An electrokinetic device for selective preconcentration and online collection based on ion concentration polarization",

abstract = "This paper reports a micro/nanofluidic device performing selective preconcentration and collection of two different charged molecules with different physicochemical properties using ion concentration polarization (ICP). By the balance between electroosmotic drag force and electrophoretic force on the molecules, two different dyes were highly preconcentrated and separated simultaneously. With the repeated geometry, ion depletion zone was stabilized and the selectively preconcentrated plug was well-defined. For subsequent on-chip or off-chip applications, pneumatic microvalve system was integrated and helped to collect the selectively preconcentrated plug into another location in a single solution. Alexa Fluor 488 was collected more than 30-fold within 30 minutes from the original sample mixture of Sulforhodamine B and Alexa Fluor 488 without further diffusion or dispersions. This integrated device provided the potential of selective preconcentration system to be used for online analytical system such as point-of-care applications.",

keywords = "Ion concentration polarization, electrokinetics, electroosmosis, electrophoresis, microfluidics, nanofluidics, pneumatic microvalve, preconcentration and separation of molecules",

author = "J. Choi and K. Huh and Moon, {D. J.} and Chae, {J. H.} and Kim, {H. C.} and Hong, {J. W.} and Kim, {S. J.}",

note = "Publisher Copyright: {\textcopyright} 2015 IEEE.; 18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015 ; Conference date: 21-06-2015 Through 25-06-2015",

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Choi, J, Huh, K, Moon, DJ, Chae, JH , Kim, HC, Hong, JW & Kim, SJ 2015, An electrokinetic device for selective preconcentration and online collection based on ion concentration polarization. in 2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015., 7180903, 2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015, Institute of Electrical and Electronics Engineers Inc., pp. 228-231, 18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015, Anchorage, United States, 21/06/15. https://doi.org/10.1109/TRANSDUCERS.2015.7180903

An electrokinetic device for selective preconcentration and online collection based on ion concentration polarization. / Choi, J.; Huh, K.; Moon, D. J. et al.
2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015. Institute of Electrical and Electronics Engineers Inc., 2015. p. 228-231 7180903 (2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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AU - Choi, J.

AU - Huh, K.

AU - Moon, D. J.

AU - Chae, J. H.

AU - Kim, H. C.

AU - Hong, J. W.

AU - Kim, S. J.

PY - 2015/8/5

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N2 - This paper reports a micro/nanofluidic device performing selective preconcentration and collection of two different charged molecules with different physicochemical properties using ion concentration polarization (ICP). By the balance between electroosmotic drag force and electrophoretic force on the molecules, two different dyes were highly preconcentrated and separated simultaneously. With the repeated geometry, ion depletion zone was stabilized and the selectively preconcentrated plug was well-defined. For subsequent on-chip or off-chip applications, pneumatic microvalve system was integrated and helped to collect the selectively preconcentrated plug into another location in a single solution. Alexa Fluor 488 was collected more than 30-fold within 30 minutes from the original sample mixture of Sulforhodamine B and Alexa Fluor 488 without further diffusion or dispersions. This integrated device provided the potential of selective preconcentration system to be used for online analytical system such as point-of-care applications.

AB - This paper reports a micro/nanofluidic device performing selective preconcentration and collection of two different charged molecules with different physicochemical properties using ion concentration polarization (ICP). By the balance between electroosmotic drag force and electrophoretic force on the molecules, two different dyes were highly preconcentrated and separated simultaneously. With the repeated geometry, ion depletion zone was stabilized and the selectively preconcentrated plug was well-defined. For subsequent on-chip or off-chip applications, pneumatic microvalve system was integrated and helped to collect the selectively preconcentrated plug into another location in a single solution. Alexa Fluor 488 was collected more than 30-fold within 30 minutes from the original sample mixture of Sulforhodamine B and Alexa Fluor 488 without further diffusion or dispersions. This integrated device provided the potential of selective preconcentration system to be used for online analytical system such as point-of-care applications.

KW - Ion concentration polarization

KW - electrokinetics

KW - electroosmosis

KW - electrophoresis

KW - microfluidics

KW - nanofluidics

KW - pneumatic microvalve

KW - preconcentration and separation of molecules

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DO - 10.1109/TRANSDUCERS.2015.7180903

M3 - Conference contribution

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T3 - 2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015

SP - 228

EP - 231

BT - 2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015

PB - Institute of Electrical and Electronics Engineers Inc.

T2 - 18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015

Y2 - 21 June 2015 through 25 June 2015

ER -

Choi J, Huh K, Moon DJ, Chae JH , Kim HC, Hong JW et al. An electrokinetic device for selective preconcentration and online collection based on ion concentration polarization. In 2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015. Institute of Electrical and Electronics Engineers Inc. 2015. p. 228-231. 7180903. (2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015). doi: 10.1109/TRANSDUCERS.2015.7180903

An electrokinetic device for selective preconcentration and online collection based on ion concentration polarization

Abstract

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