Advances in imaging instrumentation for nuclear cardiology

Jae Sung Lee, Gil Kovalski, Tali Sharir, Dong Soo Lee

Research output: Contribution to journalReview articleResearchpeer-review

5 Citations (Scopus)

Abstract

Advances in imaging instrumentation and technology have greatly contributed to nuclear cardiology. Dedicated cardiac SPECT cameras incorporating novel, highly efficient detector, collimator, and system designs have emerged with the expansion of nuclear cardiology. Solid-state radiation detectors incorporating cadmium zinc telluride, which directly convert radiation to electrical signals and yield improved energy resolution and spatial resolution and enhanced count sensitivity geometries, are increasingly gaining favor as the detector of choice for application in dedicated cardiac SPECT systems. Additionally, hybrid imaging systems in which SPECT and PET are combined with X-ray CT are currently widely used, with PET/MRI hybrid systems having also been recently introduced. The improved quantitative SPECT/CT has the potential to measure the absolute quantification of myocardial blood flow and flow reserve. Rapid development of silicon photomultipliers leads to enhancement in PET image quality and count rates. In addition, the reduction of emission–transmission mismatch artifacts via application of accurate time-of-flight information, and cardiac motion de-blurring aided by anatomical images, are emerging techniques for further improvement of cardiac PET. This article reviews recent advances such as these in nuclear cardiology imaging instrumentation and technology, and the corresponding diagnostic benefits.

Original languageEnglish
Pages (from-to)543-556
Number of pages14
JournalJournal of Nuclear Cardiology
Volume26
Issue number2
DOIs
StatePublished - 15 Apr 2019

Fingerprint

Single-Photon Emission-Computed Tomography
Cardiology
Multimodal Imaging
Radiation
Technology
X Ray Computed Tomography
Silicon
Artifacts

Keywords

  • PET
  • PET/CT
  • PET/MRI
  • SPECT
  • SPECT/CT

Cite this

Lee, Jae Sung ; Kovalski, Gil ; Sharir, Tali ; Lee, Dong Soo. / Advances in imaging instrumentation for nuclear cardiology. In: Journal of Nuclear Cardiology. 2019 ; Vol. 26, No. 2. pp. 543-556.
@article{c7fdd0ef3e2a4ad2a9a76b27de6163be,
title = "Advances in imaging instrumentation for nuclear cardiology",
abstract = "Advances in imaging instrumentation and technology have greatly contributed to nuclear cardiology. Dedicated cardiac SPECT cameras incorporating novel, highly efficient detector, collimator, and system designs have emerged with the expansion of nuclear cardiology. Solid-state radiation detectors incorporating cadmium zinc telluride, which directly convert radiation to electrical signals and yield improved energy resolution and spatial resolution and enhanced count sensitivity geometries, are increasingly gaining favor as the detector of choice for application in dedicated cardiac SPECT systems. Additionally, hybrid imaging systems in which SPECT and PET are combined with X-ray CT are currently widely used, with PET/MRI hybrid systems having also been recently introduced. The improved quantitative SPECT/CT has the potential to measure the absolute quantification of myocardial blood flow and flow reserve. Rapid development of silicon photomultipliers leads to enhancement in PET image quality and count rates. In addition, the reduction of emission–transmission mismatch artifacts via application of accurate time-of-flight information, and cardiac motion de-blurring aided by anatomical images, are emerging techniques for further improvement of cardiac PET. This article reviews recent advances such as these in nuclear cardiology imaging instrumentation and technology, and the corresponding diagnostic benefits.",
keywords = "PET, PET/CT, PET/MRI, SPECT, SPECT/CT",
author = "Lee, {Jae Sung} and Gil Kovalski and Tali Sharir and Lee, {Dong Soo}",
year = "2019",
month = "4",
day = "15",
doi = "10.1007/s12350-017-0979-8",
language = "English",
volume = "26",
pages = "543--556",
journal = "Journal of Nuclear Cardiology",
issn = "1071-3581",
publisher = "Springer New York",
number = "2",

}

Advances in imaging instrumentation for nuclear cardiology. / Lee, Jae Sung; Kovalski, Gil; Sharir, Tali; Lee, Dong Soo.

In: Journal of Nuclear Cardiology, Vol. 26, No. 2, 15.04.2019, p. 543-556.

Research output: Contribution to journalReview articleResearchpeer-review

TY - JOUR

T1 - Advances in imaging instrumentation for nuclear cardiology

AU - Lee, Jae Sung

AU - Kovalski, Gil

AU - Sharir, Tali

AU - Lee, Dong Soo

PY - 2019/4/15

Y1 - 2019/4/15

N2 - Advances in imaging instrumentation and technology have greatly contributed to nuclear cardiology. Dedicated cardiac SPECT cameras incorporating novel, highly efficient detector, collimator, and system designs have emerged with the expansion of nuclear cardiology. Solid-state radiation detectors incorporating cadmium zinc telluride, which directly convert radiation to electrical signals and yield improved energy resolution and spatial resolution and enhanced count sensitivity geometries, are increasingly gaining favor as the detector of choice for application in dedicated cardiac SPECT systems. Additionally, hybrid imaging systems in which SPECT and PET are combined with X-ray CT are currently widely used, with PET/MRI hybrid systems having also been recently introduced. The improved quantitative SPECT/CT has the potential to measure the absolute quantification of myocardial blood flow and flow reserve. Rapid development of silicon photomultipliers leads to enhancement in PET image quality and count rates. In addition, the reduction of emission–transmission mismatch artifacts via application of accurate time-of-flight information, and cardiac motion de-blurring aided by anatomical images, are emerging techniques for further improvement of cardiac PET. This article reviews recent advances such as these in nuclear cardiology imaging instrumentation and technology, and the corresponding diagnostic benefits.

AB - Advances in imaging instrumentation and technology have greatly contributed to nuclear cardiology. Dedicated cardiac SPECT cameras incorporating novel, highly efficient detector, collimator, and system designs have emerged with the expansion of nuclear cardiology. Solid-state radiation detectors incorporating cadmium zinc telluride, which directly convert radiation to electrical signals and yield improved energy resolution and spatial resolution and enhanced count sensitivity geometries, are increasingly gaining favor as the detector of choice for application in dedicated cardiac SPECT systems. Additionally, hybrid imaging systems in which SPECT and PET are combined with X-ray CT are currently widely used, with PET/MRI hybrid systems having also been recently introduced. The improved quantitative SPECT/CT has the potential to measure the absolute quantification of myocardial blood flow and flow reserve. Rapid development of silicon photomultipliers leads to enhancement in PET image quality and count rates. In addition, the reduction of emission–transmission mismatch artifacts via application of accurate time-of-flight information, and cardiac motion de-blurring aided by anatomical images, are emerging techniques for further improvement of cardiac PET. This article reviews recent advances such as these in nuclear cardiology imaging instrumentation and technology, and the corresponding diagnostic benefits.

KW - PET

KW - PET/CT

KW - PET/MRI

KW - SPECT

KW - SPECT/CT

UR - http://www.scopus.com/inward/record.url?scp=85024504033&partnerID=8YFLogxK

U2 - 10.1007/s12350-017-0979-8

DO - 10.1007/s12350-017-0979-8

M3 - Review article

VL - 26

SP - 543

EP - 556

JO - Journal of Nuclear Cardiology

JF - Journal of Nuclear Cardiology

SN - 1071-3581

IS - 2

ER -