A comparison of the performance of anatomical MRI and DTI in diagnosing carpal tunnel syndrome

Sung Hye Koh, Bong Cheol Kwon, Chanyeong Park, Su Yeon Hwang, Joon Woo Lee, Sam Soo Kim

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Purpose: To compare the performance of anatomical magnetic resonance imaging (MRI) with that of diffusion tensor imaging (DTI) in the diagnosis of carpal tunnel syndrome (CTS). Materials and methods: We performed 3T anatomical MRI and DTI on 42 patients and 42 age-matched controls. The median nerve cross-sectional area (CSA), relative median nerve signal intensity, and palmar bowing of the flexor retinaculum, assessed with anatomical MRI, and fractional anisotropy (FA) and apparent diffusion coefficient of the median nerve, assessed with DTI, were measured at four locations: the hamate level, the pisiform level (P0), the level located 1 cm proximal to the P0 level (P1), and the distal radioulnar joint level (DR). Adding the ratios and differences of the median nerve parameters between the measurements at the DR and other locations to the diagnostic parameters, we evaluated the area under the receiver operating characteristic curves (AUCs) of all the diagnostic parameters of both scans. Results: The AUCs of FA(P1) (0.814) and FA(P0) (0.824) in DTI were larger than the largest AUC for anatomical MRI, CSA(P1) (0.759). However, the receiver operating characteristics of the three parameters were not significantly different (P > 0.1). The sensitivity and specificity of CSA(P1) (76.2% and 73.8%) and FA(P1) (73.8% and 76.2%) increased after inclusive and exclusive combination to 90.5% each. Conclusion: The individual performances of both scans were not significantly different in diagnosing CTS. Measuring both CSA and FA at P1 may be useful and efficient to utilize the merits of both scans and to increase the CTS diagnostic performance.

Original languageEnglish
Pages (from-to)2065-2073
Number of pages9
JournalEuropean Journal of Radiology
Volume83
Issue number11
DOIs
StatePublished - 1 Nov 2014

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Diffusion Tensor Imaging
Carpal Tunnel Syndrome
Anisotropy
Median Nerve
Magnetic Resonance Imaging
Area Under Curve
ROC Curve
Joints
Sensitivity and Specificity

Keywords

  • Carpal tunnel syndrome
  • Diffusion tensor imaging
  • Magnetic resonance imaging
  • Median nerve
  • Wrist

Cite this

Koh, Sung Hye ; Kwon, Bong Cheol ; Park, Chanyeong ; Hwang, Su Yeon ; Lee, Joon Woo ; Kim, Sam Soo. / A comparison of the performance of anatomical MRI and DTI in diagnosing carpal tunnel syndrome. In: European Journal of Radiology. 2014 ; Vol. 83, No. 11. pp. 2065-2073.
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abstract = "Purpose: To compare the performance of anatomical magnetic resonance imaging (MRI) with that of diffusion tensor imaging (DTI) in the diagnosis of carpal tunnel syndrome (CTS). Materials and methods: We performed 3T anatomical MRI and DTI on 42 patients and 42 age-matched controls. The median nerve cross-sectional area (CSA), relative median nerve signal intensity, and palmar bowing of the flexor retinaculum, assessed with anatomical MRI, and fractional anisotropy (FA) and apparent diffusion coefficient of the median nerve, assessed with DTI, were measured at four locations: the hamate level, the pisiform level (P0), the level located 1 cm proximal to the P0 level (P1), and the distal radioulnar joint level (DR). Adding the ratios and differences of the median nerve parameters between the measurements at the DR and other locations to the diagnostic parameters, we evaluated the area under the receiver operating characteristic curves (AUCs) of all the diagnostic parameters of both scans. Results: The AUCs of FA(P1) (0.814) and FA(P0) (0.824) in DTI were larger than the largest AUC for anatomical MRI, CSA(P1) (0.759). However, the receiver operating characteristics of the three parameters were not significantly different (P > 0.1). The sensitivity and specificity of CSA(P1) (76.2{\%} and 73.8{\%}) and FA(P1) (73.8{\%} and 76.2{\%}) increased after inclusive and exclusive combination to 90.5{\%} each. Conclusion: The individual performances of both scans were not significantly different in diagnosing CTS. Measuring both CSA and FA at P1 may be useful and efficient to utilize the merits of both scans and to increase the CTS diagnostic performance.",
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A comparison of the performance of anatomical MRI and DTI in diagnosing carpal tunnel syndrome. / Koh, Sung Hye; Kwon, Bong Cheol; Park, Chanyeong; Hwang, Su Yeon; Lee, Joon Woo; Kim, Sam Soo.

In: European Journal of Radiology, Vol. 83, No. 11, 01.11.2014, p. 2065-2073.

Research output: Contribution to journalArticle

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KW - Carpal tunnel syndrome

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KW - Median nerve

KW - Wrist

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