A comparative evaluation of the KDSQ-C, AD8, and SMCQ as a cognitive screening test to be used in national medical check-ups in Korea

Ahro Kim, SangYun Kim, Kyung Won Park, Kee Hyung Park, Young Chul Youn, Dong Woo Lee, Jun-Young Lee, Jun Hong Lee, Jee Hyang Jeong, Seong Hye Choi, Hyun Jeong Han, Semi Kim, Seunghee Na, Misun Park, Hyeon Woo Yim, Dong Won Yang

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Background: Korea has a periodic general health check-up program that uses the Korean Dementia Screening Questionnaire-Cognition (KDSQ-C) as a cognitive dysfunction screening tool. The Alzheimer Disease 8 (AD8) and Subjective Memory Complaints Questionnaire (SMCQ) are also used in clinical practice. We compared the diagnostic ability of these screening questionnaires for cognitive impairment when completed by participants and their caregivers. Hence, we aimed to evaluate whether the SMCQ or AD8 is superior to the KDSQ-C and can be used as its replacement. Methods: A total of 420 participants over 65 years and their informants were recruited from 11 hospitals for this study. The patients were grouped into normal cognition, mild cognitive impairment, and dementia subgroups. The KDSQ-C, AD8, and SMCQ were completed separately by participants and their informants. Results: A receiver operating characteristic analysis of questionnaire scores completed by participants showed that the areas under the curve (AUCs) for the KDSQ-C, AD8, and SMCQ for diagnosing dementia were 0.75, 0.8, and 0.73, respectively. Regarding informant-completed questionnaires, the AD8 (AUC of 0.93), KDSQ-C (AUC of 0.92), and SMCQ (AUC of 0.92) showed good discriminability for dementia, with no differences in discriminability between the questionnaires. Conclusion: When an informant-report is possible, we recommend that the KDSQ-C continues to be used in national medical check-ups as its discriminability for dementia is not different from that of the AD8 or SMCQ. Moreover, consistent data collection using the same questionnaire is important. When an informant is not available, either the KDSQ-C or AD8 may be used. However, in the cases of patient-reports, discriminability is lower than that for informant-completed questionnaires.

Original languageEnglish
Article numbere111
JournalJournal of Korean Medical Science
Volume34
Issue number14
DOIs
StatePublished - 15 Apr 2019

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Korea
Cognition
Dementia
Area Under Curve
Alzheimer Disease 8
Surveys and Questionnaires
Aptitude

Keywords

  • Cognition
  • Dementia
  • Questionnaire
  • Self-Assessment
  • Self-Report

Cite this

Kim, Ahro ; Kim, SangYun ; Park, Kyung Won ; Park, Kee Hyung ; Youn, Young Chul ; Lee, Dong Woo ; Lee, Jun-Young ; Lee, Jun Hong ; Jeong, Jee Hyang ; Choi, Seong Hye ; Han, Hyun Jeong ; Kim, Semi ; Na, Seunghee ; Park, Misun ; Yim, Hyeon Woo ; Yang, Dong Won. / A comparative evaluation of the KDSQ-C, AD8, and SMCQ as a cognitive screening test to be used in national medical check-ups in Korea. In: Journal of Korean Medical Science. 2019 ; Vol. 34, No. 14.
@article{ecefcd4759d74131a693e6cb4b8dc181,
title = "A comparative evaluation of the KDSQ-C, AD8, and SMCQ as a cognitive screening test to be used in national medical check-ups in Korea",
abstract = "Background: Korea has a periodic general health check-up program that uses the Korean Dementia Screening Questionnaire-Cognition (KDSQ-C) as a cognitive dysfunction screening tool. The Alzheimer Disease 8 (AD8) and Subjective Memory Complaints Questionnaire (SMCQ) are also used in clinical practice. We compared the diagnostic ability of these screening questionnaires for cognitive impairment when completed by participants and their caregivers. Hence, we aimed to evaluate whether the SMCQ or AD8 is superior to the KDSQ-C and can be used as its replacement. Methods: A total of 420 participants over 65 years and their informants were recruited from 11 hospitals for this study. The patients were grouped into normal cognition, mild cognitive impairment, and dementia subgroups. The KDSQ-C, AD8, and SMCQ were completed separately by participants and their informants. Results: A receiver operating characteristic analysis of questionnaire scores completed by participants showed that the areas under the curve (AUCs) for the KDSQ-C, AD8, and SMCQ for diagnosing dementia were 0.75, 0.8, and 0.73, respectively. Regarding informant-completed questionnaires, the AD8 (AUC of 0.93), KDSQ-C (AUC of 0.92), and SMCQ (AUC of 0.92) showed good discriminability for dementia, with no differences in discriminability between the questionnaires. Conclusion: When an informant-report is possible, we recommend that the KDSQ-C continues to be used in national medical check-ups as its discriminability for dementia is not different from that of the AD8 or SMCQ. Moreover, consistent data collection using the same questionnaire is important. When an informant is not available, either the KDSQ-C or AD8 may be used. However, in the cases of patient-reports, discriminability is lower than that for informant-completed questionnaires.",
keywords = "Cognition, Dementia, Questionnaire, Self-Assessment, Self-Report",
author = "Ahro Kim and SangYun Kim and Park, {Kyung Won} and Park, {Kee Hyung} and Youn, {Young Chul} and Lee, {Dong Woo} and Jun-Young Lee and Lee, {Jun Hong} and Jeong, {Jee Hyang} and Choi, {Seong Hye} and Han, {Hyun Jeong} and Semi Kim and Seunghee Na and Misun Park and Yim, {Hyeon Woo} and Yang, {Dong Won}",
year = "2019",
month = "4",
day = "15",
doi = "10.3346/jkms.2019.34.e111",
language = "English",
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journal = "Journal of Korean medical science",
issn = "1011-8934",
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Kim, A, Kim, S, Park, KW, Park, KH, Youn, YC, Lee, DW, Lee, J-Y, Lee, JH, Jeong, JH, Choi, SH, Han, HJ, Kim, S, Na, S, Park, M, Yim, HW & Yang, DW 2019, 'A comparative evaluation of the KDSQ-C, AD8, and SMCQ as a cognitive screening test to be used in national medical check-ups in Korea', Journal of Korean Medical Science, vol. 34, no. 14, e111. https://doi.org/10.3346/jkms.2019.34.e111

A comparative evaluation of the KDSQ-C, AD8, and SMCQ as a cognitive screening test to be used in national medical check-ups in Korea. / Kim, Ahro; Kim, SangYun; Park, Kyung Won; Park, Kee Hyung; Youn, Young Chul; Lee, Dong Woo; Lee, Jun-Young; Lee, Jun Hong; Jeong, Jee Hyang; Choi, Seong Hye; Han, Hyun Jeong; Kim, Semi; Na, Seunghee; Park, Misun; Yim, Hyeon Woo; Yang, Dong Won.

In: Journal of Korean Medical Science, Vol. 34, No. 14, e111, 15.04.2019.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - A comparative evaluation of the KDSQ-C, AD8, and SMCQ as a cognitive screening test to be used in national medical check-ups in Korea

AU - Kim, Ahro

AU - Kim, SangYun

AU - Park, Kyung Won

AU - Park, Kee Hyung

AU - Youn, Young Chul

AU - Lee, Dong Woo

AU - Lee, Jun-Young

AU - Lee, Jun Hong

AU - Jeong, Jee Hyang

AU - Choi, Seong Hye

AU - Han, Hyun Jeong

AU - Kim, Semi

AU - Na, Seunghee

AU - Park, Misun

AU - Yim, Hyeon Woo

AU - Yang, Dong Won

PY - 2019/4/15

Y1 - 2019/4/15

N2 - Background: Korea has a periodic general health check-up program that uses the Korean Dementia Screening Questionnaire-Cognition (KDSQ-C) as a cognitive dysfunction screening tool. The Alzheimer Disease 8 (AD8) and Subjective Memory Complaints Questionnaire (SMCQ) are also used in clinical practice. We compared the diagnostic ability of these screening questionnaires for cognitive impairment when completed by participants and their caregivers. Hence, we aimed to evaluate whether the SMCQ or AD8 is superior to the KDSQ-C and can be used as its replacement. Methods: A total of 420 participants over 65 years and their informants were recruited from 11 hospitals for this study. The patients were grouped into normal cognition, mild cognitive impairment, and dementia subgroups. The KDSQ-C, AD8, and SMCQ were completed separately by participants and their informants. Results: A receiver operating characteristic analysis of questionnaire scores completed by participants showed that the areas under the curve (AUCs) for the KDSQ-C, AD8, and SMCQ for diagnosing dementia were 0.75, 0.8, and 0.73, respectively. Regarding informant-completed questionnaires, the AD8 (AUC of 0.93), KDSQ-C (AUC of 0.92), and SMCQ (AUC of 0.92) showed good discriminability for dementia, with no differences in discriminability between the questionnaires. Conclusion: When an informant-report is possible, we recommend that the KDSQ-C continues to be used in national medical check-ups as its discriminability for dementia is not different from that of the AD8 or SMCQ. Moreover, consistent data collection using the same questionnaire is important. When an informant is not available, either the KDSQ-C or AD8 may be used. However, in the cases of patient-reports, discriminability is lower than that for informant-completed questionnaires.

AB - Background: Korea has a periodic general health check-up program that uses the Korean Dementia Screening Questionnaire-Cognition (KDSQ-C) as a cognitive dysfunction screening tool. The Alzheimer Disease 8 (AD8) and Subjective Memory Complaints Questionnaire (SMCQ) are also used in clinical practice. We compared the diagnostic ability of these screening questionnaires for cognitive impairment when completed by participants and their caregivers. Hence, we aimed to evaluate whether the SMCQ or AD8 is superior to the KDSQ-C and can be used as its replacement. Methods: A total of 420 participants over 65 years and their informants were recruited from 11 hospitals for this study. The patients were grouped into normal cognition, mild cognitive impairment, and dementia subgroups. The KDSQ-C, AD8, and SMCQ were completed separately by participants and their informants. Results: A receiver operating characteristic analysis of questionnaire scores completed by participants showed that the areas under the curve (AUCs) for the KDSQ-C, AD8, and SMCQ for diagnosing dementia were 0.75, 0.8, and 0.73, respectively. Regarding informant-completed questionnaires, the AD8 (AUC of 0.93), KDSQ-C (AUC of 0.92), and SMCQ (AUC of 0.92) showed good discriminability for dementia, with no differences in discriminability between the questionnaires. Conclusion: When an informant-report is possible, we recommend that the KDSQ-C continues to be used in national medical check-ups as its discriminability for dementia is not different from that of the AD8 or SMCQ. Moreover, consistent data collection using the same questionnaire is important. When an informant is not available, either the KDSQ-C or AD8 may be used. However, in the cases of patient-reports, discriminability is lower than that for informant-completed questionnaires.

KW - Cognition

KW - Dementia

KW - Questionnaire

KW - Self-Assessment

KW - Self-Report

UR - http://www.scopus.com/inward/record.url?scp=85064833656&partnerID=8YFLogxK

U2 - 10.3346/jkms.2019.34.e111

DO - 10.3346/jkms.2019.34.e111

M3 - Article

VL - 34

JO - Journal of Korean medical science

JF - Journal of Korean medical science

SN - 1011-8934

IS - 14

M1 - e111

ER -