A case of breakthrough COVID-19 during hydroxychloroquine maintenance

Byeong Yun Ahn; Chang Kyung Kang; Jong Do Seo; Pyoeng Gyun Choe; Sang Hoon Song; Wan Beom Park; Sang Won Park; Nam Joong Kim; Myoung don Oh

doi:10.3346/JKMS.2020.35.E231

A case of breakthrough COVID-19 during hydroxychloroquine maintenance

Byeong Yun Ahn, Chang Kyung Kang, Jong Do Seo, Pyoeng Gyun Choe, Sang Hoon Song, Wan Beom Park, Sang Won Park, Nam Joong Kim, Myoung don Oh

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

There have been controversies on the prophylactic effect of hydroxychloroquine against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). We describe a patient, 60-year old Korean woman, with coronavirus disease 2019 (COVID-19) who had been taking hydroxychloroquine for 6 months. Her serum and saliva concentrations of hydroxychloroquine were 280 μg/L and 4,890 μg/L, respectively. The present case raises concerns on hydroxychloroquine's role as a prophylactic agent for COVID-19.

Original language	English
Article number	e231
Journal	Journal of Korean Medical Science
Volume	35
Issue number	24
DOIs	https://doi.org/10.3346/JKMS.2020.35.E231
State	Published - 22 Jun 2020

Bibliographical note

Publisher Copyright:
© 2020 The Korean Academy of Medical Sciences.

Keywords

COVID-19
Hydroxychloroquine
Prophylaxis
SARS-CoV-2

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10.3346/JKMS.2020.35.E231

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title = "A case of breakthrough COVID-19 during hydroxychloroquine maintenance",

abstract = "There have been controversies on the prophylactic effect of hydroxychloroquine against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). We describe a patient, 60-year old Korean woman, with coronavirus disease 2019 (COVID-19) who had been taking hydroxychloroquine for 6 months. Her serum and saliva concentrations of hydroxychloroquine were 280 μg/L and 4,890 μg/L, respectively. The present case raises concerns on hydroxychloroquine's role as a prophylactic agent for COVID-19.",

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AU - Seo, Jong Do

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AU - Song, Sang Hoon

AU - Park, Wan Beom

AU - Park, Sang Won

AU - Kim, Nam Joong

AU - Oh, Myoung don

PY - 2020/6/22

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N2 - There have been controversies on the prophylactic effect of hydroxychloroquine against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). We describe a patient, 60-year old Korean woman, with coronavirus disease 2019 (COVID-19) who had been taking hydroxychloroquine for 6 months. Her serum and saliva concentrations of hydroxychloroquine were 280 μg/L and 4,890 μg/L, respectively. The present case raises concerns on hydroxychloroquine's role as a prophylactic agent for COVID-19.

AB - There have been controversies on the prophylactic effect of hydroxychloroquine against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). We describe a patient, 60-year old Korean woman, with coronavirus disease 2019 (COVID-19) who had been taking hydroxychloroquine for 6 months. Her serum and saliva concentrations of hydroxychloroquine were 280 μg/L and 4,890 μg/L, respectively. The present case raises concerns on hydroxychloroquine's role as a prophylactic agent for COVID-19.

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KW - Hydroxychloroquine

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A case of breakthrough COVID-19 during hydroxychloroquine maintenance

Abstract

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